CROs - A Brief History

Contract research organizations or CRO had steadilyand developmental research, new obstacles like
gained success and achieved a top position. With itsfunding issues and patent problems harrowed the
successful foray into the pharma and biotechnologycompanies. The year 2008 also saw major cost
sector, it had translated into profits for investors. Thiscutting moves like employee lay offs, postponing
all is now a thing of past and no longer prevails, theprojects to the next year, change the company focus
scene has completely changed.from product development to later-stage drug
What paved way for their winning streak, wasdevelopment programs.
outsourcing projects meant cutting costs forOwing to all this, the CRO's faced the flak and resulted
pharmaceutical companies; workforce and revenuein stock prices hitting an all time low and their downfall
could be re-directed towards other avenues and aidedbegan. There is another side to it, sacking of
the research process. CRO's initiated researched,employees from the pharmaceutical industry meant
prepared reports at every stage, conducted detailedthat more workforce ready to work for lower salaries
quality analysis and ensured that all was in sync withwas made available to the CRO's, but it also meant
the rules and procedures laid down by FDA.there was a constant pressure on the CRO's to
CRO's offer a wide range of services to thesurvive and emerge as a successful venture.
pharmaceutical companies; right from product planningThe highlight and a point to be noted is rather than
like drug development, drug formulation, clinical researchfocusing on cost of human resources, companies need
including conducting clinical trials, clinical research andto ensure a quality of staff hired.
other stages like Sample collection, medical writingIf the trend continues, it will eventually lead to many
services, preclinical, toxicology, and clinical laboratorymore issues and problems and will affect not only the
services. Prepare extensive documentation requiredeconomy but will also result in lesser research and
for the approval like Abbreviated New Drugdevelopment; the latter issue is more important as it
Application (ANDA), or Biologic License Applicationaddressed the health industry that is important and vital
(BLA). CRO's efficiently and more importantlyfor any nation.
cost-effectively handled everything.One more hassle is the struggle and danger awaiting
However, from 2008, the trend changed and hiringthe workers belonging to the clinical research sector
services of Contract research organizations declinedand medical sectors is 'What next'? They have to
and came to a grinding halt. There were major layoffsexplore different avenues to keep pace with the
across the pharmaceutical industry.changing trends and situation or face lay-off and
The guidance affected everything. Though theunemployment or work for lesser salary.
companies continued its pursuit of new drug discovery